Trials platform
Run In silico trials on virtual human populations to test efficacy and cardiac safety before you enroll a single patient.
How Trials works
1
Customise heart populations.
Apply treatments.
2
Extract biomarkers and data of interest from simulated ECGs
3
Compare Clinical trials
See virtual patient groups statistics
Access subject specific data
Key benefits
Define your compound with precision and model any dosing strategy, including off-label, supra-therapeutic and overdose scenarios you can’t safely test in humans.
Build virtual patient cohorts based on real-world or study-specific criteria.
Match your target label by refining your group of patients: extend, characterise and evaluate subgroups with a few clicks, including age, sex or comorbidities.
Test multiple scenarios in hours instead of months, with no recruitment delays, no patient risk and full reproducibility across runs.
From a single virtual human to an entire virtual human population: test the untestable and access hidden biomarkers, such as transient calcium, that real-world trials are rarely able to measure.
Compare simulations with clinical data and generate professional, structured clinical trials reports.
How else can V.HEART
What we offer
Leverage clinical trials simulation and access traditionally hidden biomarkers
Calcium Transient - inspect intracellular Ca²⁺ dynamics underlying contraction and pro-arrhythmic behaviour, a mechanistic layer beneath the ECG
ECG leads grid - read simulated 12-lead ECGs and quantify ΔQT / ΔQTc per virtual patient, the endpoints used in thorough-QT assessment
Integration with external trials results - benchmark simulated ΔQTc against your own clinical or thorough-QT data for a like-for-like comparison
Biomarker selection - choose from standard and traditionally hidden biomarkers (e.g. APD, triangulation) to match your study’s safety endpoints
How does our technology work?
ELEM’s Biosimulation technology combines patient-specific data, high-performance physics-based simulation, and advanced computational modelling to create healthcare digital twins for your clinical trials.
Leveraging clinical trials simulation enables predictive insights, supporting faster, safer, and data-driven clinical decisions.
Get started with ELEM Clinical Trials Simulation Platform
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