April 29, 2024
In this study, we present a systematic evaluation of CRT pacing protocols through an in silico clinical trial based on a patient-specific digital twin cohort of Left Bundle Branch Block (LBBB)
April 18, 2024
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS. While current computational methodologies focus on predicting the incidence of proarrhythmic events after drug administration, the objective of
April 18, 2024
This study represents a significant step towardsintegrating in silico technologies into real clinical contexts, providing a robust framework for improving aortic stenosis diagnosis and the design of
November 10, 2023
We propose a device consisting of a strut structure placed at the base of the treated artery to model the potential risk of cerebral embolisms caused by dislodged debris of varying sizes. This work
September 14, 2023
The proposed workflow for in silico clinical drug cardiotoxicity trials allows for reproducing the complex behavior of cardiac electrophysiology in a varied population, in a matter of a few days as
April 1, 2023
The objective of the present work is to develop a highly detailed 3D electromechanical model of the human atria in order to assess how atrial fibrillation-induced electrical remodelling affects
March 1, 2023
REPRODUCTIVE TOXICOLOGY JOURNAL. To help to identify the key data gaps, this paper aims to present (a) how transplacental EDs modify immune system and brain development, and (b) how these mechanisms
February 13, 2023
The aim of this work was to analyze the influence of sex hormones and anatomical details (trabeculations and false tendons) on the electrophysiology of healthy human
April 16, 2022
We hypothesized in NSS the heart would be more likely to receive hypoxemic blood than the brain due to the proximity of the coronary arteries to the aortic annulus. To test this, we conducted a
April 14, 2022
By combining well curated, prospectively acquired longitudinal data of the NSHD with novel CMR–ECGI data and sharing these results and associated pipelines with the CMR community, MyoFit46 seeks to
September 10, 2021
Using a translational approach in pigs and patients with established myocardial infarction, we tested and validated a novel 3D methodology to assess ventricular scar using custom transmural criteria
July 3, 2020
In this work we present a robust interface coupling algorithm called Compact Interface quasi-Newton (CIQN). It is designed for computationally intensive applications using an MPI multi-code