Publications Archives - Page 2 of 16

Advancing aortic stenosis assessment: validation of fluid-structure interaction models against 4D flow MRI data

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April 18, 2024

Advancing aortic stenosis assessment: validation of fluid-structure interaction models against 4D flow MRI data

This study represents a significant step towardsintegrating in silico technologies into real clinical contexts, providing a robust framework for improving aortic stenosis diagnosis and the design of

A 3D Electromechanical Model of the Human Atria: A Realistic Framework for the Study of Atrial Fibrillation

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April 1, 2023

A 3D Electromechanical Model of the Human Atria: A Realistic Framework for the Study of Atrial Fibrillation

The objective of the present work is to develop a highly detailed 3D electromechanical model of the human atria in order to assess how atrial fibrillation-induced electrical remodelling affects

Impact of endocrine disruptors from mother’s diet on immuno-hormonal orchestration of brain development and introduction of the virtual human twin tool

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March 1, 2023

Impact of endocrine disruptors from mother’s diet on immuno-hormonal orchestration of brain development and introduction of the virtual human twin tool

REPRODUCTIVE TOXICOLOGY JOURNAL. To help to identify the key data gaps, this paper aims to present (a) how transplacental EDs modify immune system and brain development, and (b) how these mechanisms

HPC Framework for Performing in Silico Trials Using a 3D Virtual Human Cardiac Population as Means to Assess Drug-Induced Arrhythmic Risk

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September 2, 2022

HPC Framework for Performing in Silico Trials Using a 3D Virtual Human Cardiac Population as Means to Assess Drug-Induced Arrhythmic Risk

Following the 3 R's principles of animal research-replacement, reduction, and refinement-a high-performance computational framework was produced to generate a platform to perform human cardiac